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1

Programmable DNA Switches and their Applications

Harroun, Scott G, Prévost-Tremblay, Carl, Lauzon, Dominic, Desrosiers, Arnaud, Wang, Xiaomeng, Pedro, Liliana, Vallée-Bélisle, Alexis

Journal:

Year:

2018

Language:

english

File:

PDF, 5.80 MB

english, 2018

2

Structure-switching biosensors: inspired by Nature

Alexis Vallée-Bélisle, Kevin W Plaxco

Journal:

Current Opinion in Structural Biology

Year:

2010

Language:

english

File:

PDF, 422 KB

english, 2010

3

raf RBD and Ubiquitin Proteins Share Similar Folds, Folding Rates and Mechanisms Despite Having Unrelated Amino Acid Sequences †

Vallée-Bélisle, Alexis, Turcotte, Jean-François, Michnick, Stephen W.

Journal:

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

4

General Strategy to Introduce pH-Induced Allostery in DNA-Based Receptors to Achieve Controlled Release of Ligands

Porchetta, Alessandro, Idili, Andrea, Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Year:

2015

Language:

english

File:

PDF, 927 KB

english, 2015

5

Employing the Metabolic “Branch Point Effect” to Generate an All-or-None, Digital-like Response in Enzymatic Outputs and Enzyme-Based Sensors

Rafael, Sandra Perez, Vallée-Bélisle, Alexis, Fabregas, Esteve, Plaxco, Kevin, Palleschi, Giuseppe, Ricci, Francesco

Journal:

Analytical Chemistry

Year:

2012

Language:

english

File:

PDF, 746 KB

english, 2012

6

Using Nature’s “Tricks” To Rationally Tune the Binding Properties of Biomolecular Receptors

Ricci, Francesco, Vallée-Bélisle, Alexis, Simon, Anna J., Porchetta, Alessandro, Plaxco, Kevin W.

Journal:

Accounts of Chemical Research

Year:

2016

Language:

english

File:

PDF, 2.58 MB

english, 2016

7

Aptamer-based liposomes improve specific drug loading and release

Plourde, Kevin, Derbali, Rabeb Mouna, Desrosiers, Arnaud, Dubath, Céline, Vallée-Bélisle, Alexis, Leblond, Jeanne

Journal:

Journal of Controlled Release

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

8

An electrochemical DNA-based immunoassay that employs steric hindrance to detect small molecules directly in whole blood

Mahshid, Sahar Sadat, Ricci, Francesco, Kelley, Shana O., Vallée-Bélisle, Alexis

Journal:

Year:

2017

Language:

english

File:

PDF, 566 KB

english, 2017

9

Biomolecular Steric Hindrance Effects Are Enhanced on Nanostructured Microelectrodes

Mahshid, Sahar Sadat, Vallée-Bélisle, Alexis, Kelley, Shana O.

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 889 KB

english, 2017

10

Entropic and Electrostatic Effects on the Folding Free Energy of a Surface-Attached Biomolecule: An Experimental and Theoretical Study

Watkins, Herschel M., Vallée-Bélisle, Alexis, Ricci, Francesco, Makarov, Dmitrii E., Plaxco, Kevin W.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

11

A comparison of the folding kinetics of a small, artificially selected DNA aptamer with those of equivalently simple naturally occurring proteins

Lawrence, Camille, Vallée-Bélisle, Alexis, Pfeil, Shawn H., de Mornay, Derek, Lipman, Everett A., Plaxco, Kevin W.

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 430 KB

english, 2014

12

Using Distal-Site Mutations and Allosteric Inhibition To Tune, Extend, and Narrow the Useful Dynamic Range of Aptamer-Based Sensors

Porchetta, Alessandro, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Ricci, Francesco

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

13

Controlling Hybridization Chain Reactions with pH

Idili, Andrea, Porchetta, Alessandro, Amodio, Alessia, Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

14

Multiple Tryptophan Probes Reveal that Ubiquitin Folds via a Late Misfolded Intermediate

Alexis Vallée-Bélisle, Stephen W. Michnick

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.39 MB

english, 2007

15

Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes

Fan Xia, Xiaolei Zuo, Renqiang Yang, Yi Xiao, Di Kang, Alexis Vallée-Bélisle, Xiong Gong, Jonathan D. Yuen, Ben B. Y. Hsu, Alan J. Heeger and Kevin W. Plaxco

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

16

A DNA Nanodevice That Loads and Releases a Cargo with Hemoglobin-Like Allosteric Control and Cooperativity

Mariottini, Davide, Idili, Andrea, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Ricci, Francesco

Journal:

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

17

Re-engineering Electrochemical Biosensors To Narrow or Extend Their Useful Dynamic Range

Di Kang, Dr. Alexis Vallée-Bélisle, Alessandro Porchetta, Prof. Dr. Kevin W. Plaxco, Dr. Francesco Ricci

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 625 KB

english, 2012

18

Engineering Biosensors with Extended, Narrowed, or Arbitrarily Edited Dynamic Range

Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

19

Programmable pH-Triggered DNA Nanoswitches

Idili, Andrea, Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 791 KB

english, 2014

20

Electrochemical plasmonic sensing system for highly selective multiplexed detection of biomolecules based on redox nanoswitches

Dallaire, Anne-Marie, Patskovsky, Sergiy, Vallée-Bélisle, Alexis, Meunier, Michel

Journal:

Biosensors and Bioelectronics

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

21

DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors

Kang, Di, White, Ryan J, Xia, Fan, Zuo, Xiaolei, Vallée-Bélisle, Alexis, Plaxco, Kevin W

Journal:

NPG Asia Materials

Year:

2012

Language:

english

File:

PDF, 566 KB

english, 2012

22

Quantification of Transcription Factor Binding in Cell Extracts Using an Electrochemical, Structure-Switching Biosensor

Bonham, Andrew J., Hsieh, Kuangwen, Ferguson, B. Scott, Vallée-Bélisle, Alexis, Ricci, Francesco, Soh, H. Tom, Plaxco, Kevin W.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 733 KB

english, 2012

23

A Disorder-Based Strategy for the Introduction of Allosteric, “Hill-Type” Cooperativity into Artificial Receptors

Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Watkins, Herschel M., Plaxco, Kevin W.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

24

Thermodynamic Basis for Engineering High-Affinity, High-Specificity Binding-Induced DNA Clamp Nanoswitches

Idili, Andrea, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

25

Steric Hindrance Assay for Secreted Factors in Stem Cell Culture

Zhou, Wendi, Mahshid, Sahar S., Wang, Weijia, Vallée-Bélisle, Alexis, Zandstra, Peter W., Sargent, Edward H., Kelley, Shana O.

Journal:

Year:

2017

Language:

english

File:

PDF, 764 KB

english, 2017

26

A Peptide-Mediated Electrochemical Steric Hindrance Assay for One-Step Detection of HIV Antibodies

Mahshid, Sahar Sadat Sadat, Mahshid, Sara, Vallée-Bélisle, Alexis, Kelley, Shana O.

Journal:

Analytical Chemistry

Year:

2019

File:

PDF, 487 KB

2019

27

Visualizing transient protein-folding intermediates by tryptophan-scanning mutagenesis

Vallée-Bélisle, Alexis, Michnick, Stephen W

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1017 KB

english, 2012

28

Re-engineering Electrochemical Biosensors To Narrow or Extend Their Useful Dynamic Range

Di Kang, Dr. Alexis Vallée-Bélisle, Alessandro Porchetta, Prof. Dr. Kevin W. Plaxco, Dr. Francesco Ricci

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 637 KB

english, 2012

29

Principles for the Rational Design of Allosterically Cooperative Biomolecular Receptors

Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Watkins, Herschel M., Plaxco, Kevin W.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 110 KB

english, 2014

30

Determining the folding and binding free energy of DNA-based nanodevices and nanoswitches using urea titration curves

Idili, Andrea, Ricci, Francesco, Vallée-Bélisle, Alexis

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 1.97 MB

english, 2017

31

Bioelectrochemical Switches for the Quantitative Detection of Antibodies Directly in Whole Blood

Vallée-Bélisle, Alexis, Ricci, Francesco, Uzawa, Takanori, Xia, Fan, Plaxco, Kevin W.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

32

Biomimetic glass nanopores employing aptamer gates responsive to a small molecule

Abelow, Alexis E., Schepelina, Olga, White, Ryan J., Vallée-Bélisle, Alexis, Plaxco, Kevin W., Zharov, Ilya

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

33

High-Precision, In Vitro Validation of the Sequestration Mechanism for Generating Ultrasensitive Dose-Response Curves in Regulatory Networks

Ricci, Francesco, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Fan, Chunhai

Journal:

PLoS Computational Biology

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

34

Enzyme-Operated DNA-Based Nanodevices

Del Grosso, Erica, Dallaire, Anne-Marie, Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Year:

2015

Language:

english

File:

PDF, 890 KB

english, 2015

35

A Modular, DNA-Based Beacon for Single-Step Fluorescence Detection of Antibodies and Other Proteins

Ranallo, Simona, Rossetti, Marianna, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Angewandte Chemie

Year:

2015

Language:

english

File:

PDF, 2.74 MB

english, 2015

36

Nature-inspired DNA switches: applications in medicine

Desrosiers, Arnaud, Vallée-Bélisle, Alexis

Journal:

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

37

Engineering biosensors with dual programmable dynamic ranges

Wei, Benmei, Zhang, Juntao, Ou, Xiaowen, Lou, Xiaoding, Xia, Fan, Vallée-Bélisle, Alexis

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 448 KB

english, 2018

38

Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors

Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 967 KB

english, 2014

39

Using the Population-Shift Mechanism to Rationally Introduce “Hill-type” Cooperativity into a Normally Non-Cooperative Receptor

Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Watkins, Herschel M., Plaxco, Kevin W.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 955 KB

english, 2014

40

A Modular, DNA-Based Beacon for Single-Step Fluorescence Detection of Antibodies and Other Proteins

Ranallo, Simona, Rossetti, Marianna, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 2.75 MB

english, 2015

41

Antibody-powered nucleic acid release using a DNA-based nanomachine

Ranallo, Simona, Prévost-Tremblay, Carl, Idili, Andrea, Vallée-Bélisle, Alexis, Ricci, Francesco

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.36 MB

english, 2017

42

Rational Design of Allosteric Inhibitors and Activators Using the Population-Shift Model: In Vitro Validation and Application to an Artificial Biosensor

Ricci, Francesco, Vallée-Bélisle, Alexis, Porchetta, Alessandro, Plaxco, Kevin W.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 772 KB

english, 2012

43

Using the Population-Shift Mechanism to Rationally Introduce “Hill-type” Cooperativity into a Normally Non-Cooperative Receptor

Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Watkins, Herschel M., Plaxco, Kevin W.

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 943 KB

english, 2014

44

Programmable, quantitative, DNA nanothermometers

Gareau, David, Desrosiers, Arnaud Laurent Thomas, Vallée-Bélisle, Alexis

Journal:

Year:

2016

Language:

english

File:

PDF, 2.01 MB

english, 2016

45

Protein folding: Defining a “standard” set of experimental conditions and a preliminary kinetic data set of two-state proteins

Karen L. Maxwell, David Wildes, Arash Zarrine-Afsar, Miguel A. De Los Rios, Andrew G. Brown, Claire T. Friel, Linda Hedberg, Jia-Cherng Horng, Diane Bona, Erik J. Miller, Alexis Vallée-Bélisle, Ewan R

Journal:

Protein Science

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

46

Allosterically Tunable, DNA-Based Switches Triggered by Heavy Metals

Porchetta, Alessandro, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Ricci, Francesco

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 553 KB

english, 2013

47

Electrochemical structure-switching sensing using nanoplasmonic devices

Patskovsky, Sergiy, Dallaire, Anne-Marie, Blanchard-Dionne, Andre-Pierre, Vallée-Bélisle, Alexis, Meunier, Michel

Journal:

Annalen der Physik

Year:

2015

Language:

english

File:

PDF, 746 KB

english, 2015

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